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Description
Mouse Anti-Human CD209 Antibody (S-2881)Product Specification Host Mouse Antigen CD209 Synonyms CD209 antigen; C type lectin domain family 4 member L; Dendritic cell specific ICAM 3 grabbing non integrin 1 (DC SIGN; DC SIGN1); CLEC4L Location Cell membrane Accession Q9NNX6 Clone Number S 2881 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample Human peripheral blood monocyte derived dendritic cells Purification Protein A Concentration 2 mg ml Conjugation
Product Specification
| Host | Mouse |
| Antigen | CD209 |
| Synonyms | CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1 (DC-SIGN; DC-SIGN1); CLEC4L |
| Location | Cell membrane |
| Accession | Q9NNX6 |
| Clone Number | S-2881 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human peripheral blood monocyte-derived dendritic cells |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD209 (also called DC-SIGN) is a C-type lectin transmembrane receptor encoded by the CD209 gene, expressed predominantly on immature dendritic cells and macrophages; its extracellular carbohydrate-recognition domain binds high-mannose glycans on a broad spectrum of pathogens—ranging from HIV-1, HCV, Ebola, Dengue and SARS-CoV to mycobacteria—thereby functioning as a pattern-recognition receptor that triggers pathogen internalization, lysosomal degradation and subsequent MHC-II-restricted antigen presentation to prime T cells, while also mediating dendritic cell rolling on ICAM-2/ICAM-3 for migration and immune-synapse formation, with polymorphisms in its neck region linked to altered susceptibility to HIV-1 and SARS severity.
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Exchange/Return Notes
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4.2 ★★★★★
Based on 2456 reviews
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Product Reviews
★★★★★ 4
IT WORKS, IT REALLY WORKS!
Size: 16oz, Size: 16oz
I carry a tire plug kit in my van. Low pressure light came on and quickly made my way to air pump. Checked out tire and was at least a 5/16" bolt right between tread, very easy to locate (hissing). Inflated tire, prepared plug, pulled out bolt, inserted plug done. Almost home light came on again. Used water soap and plug was still leaking. Tried double plug and still leaking, but would take days to trigger low pressure light. Tire still had decent tread and didn't have facilities to patch, so got a can of fix a flat. I have never believed in this stuff, but it worked. No low pressure warnings for about a month. Around here they would charge $50 for a patch, 2 .25 cent soft rubber plugs and fix a flat, problem resolved!
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Reviewed in the United States on August 25, 2025
★★★★★ 5
Buy it! Lifesaver!
Size: 16oz
Yes, buy it when you don't have a spare tire because you will need it!
I live in Florida and flat tires are just part of living here!
Saved my life twice already and is absolutely self explaining!
Cheaper then a spare tire, lighter than one too! Just throw it in your trunk and best case you will never need it but just in case!
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Reviewed in the United States on May 23, 2026
★★★★★ 1
Difficult to use and eventually hose end broke
Size: 24oz, Size: 24oz
I purchased this can of Fix-A-Flat to fix, what I believe, is a rim leak on my truck tire which needs to be filled once every week or so. When I attempted to use the product I let some air out of the tire (down to 25 psi) so it would be easier to dispense the contents. The instructions on the can say to have the valve on the tire at the 6 o'clock...which I did as well.
When I attempted to make the connection using the swivel connector on the can's hose it was difficult. The hose on the can is very short and stiff and because it came coiled in the can's lid, did not want to straighten out making connecting it to the tire a very awkward process. It was hard to screw the hose end on the valve without it binding so it felt like it was cross-threading. I have machined aluminum valve caps and they go one very easily so I know the threads on the tire's valve stem are clean.
I finally did get it on and when I attempted to dispense the contents it filled the hose but that was about it. I could not see any contents flowing thru the hose at all. I assumed it was not on far enough so I took it off to try again and the contents sprayed everywhere showing it was indeed under pressure....just not going into the tire. After multiple tries the hose end eventually just broke off and stayed on the tire's valve stem. I was able to get it off, but at this point the can is useless to me.
Obviously I cannot and will not recommend this product. I have used this product before and had success, but that was when the hose was longer and wired to the side of the can making it much easier to use, versus how they are shipped now. I would recommend going with another product or possible going to a box store (which is what I plan to do) to find one that does not have this design. At the very least, if you do choose to disregard this review, I would try it with the tire's valve stem at the 3 or 9 o'clock position which might make it easier to thread the hose end on to the valve stem,.
Also, if you choose to go this route you might just be throwing your money away. I attempted to get a refund from Amazon and was directed to the manufacture's web site. From there you are directed to use the 800 number of leave a general message that is in no way connected to your Amazon purchase. Past experience tells me it will not be an easy process so it looks like I am out the $12.
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Reviewed in the United States on March 10, 2024
★★★★★ 5
This is a necessity for anyone that tries a car!!
Size: 20oz 6pk
I haven’t used this yet, but I bought a case to give to my family members. My friend who came outside to a flat tire. It was a Sunday in Utah so there was really no one that could fix it. Walmart told her to get this product. She had to drive home immediately following using this product (300 miles) It has been over two months now and my niece is still driving on that tire. It was a brand new tire that was costly so she decided to just wait and see how long this product will work. Great gift for anyone in the family that drives. This does not work on a blown tire. If you wake up in the morning and your tire is flat, or you get out of class and your tire is flat, just use this product and no calls need to be made.
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Reviewed in the United States on October 14, 2025
★★★★★ 5
Great product and great service
Size: 16oz
By all accounts it's a great product! It arrived and I feel more confident having it with me in the car.
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Reviewed in the United States on April 28, 2026